MAG-pie Alert!… #2 TOXICITY OF IRON
https://www.researchgate.net/…/11/3171S.full.pdf+html
THINGS THAT GO “BUMP” IN THE NIGHT…
My advice, grab your seatbelt… this is likely going to be a brief, bumpy, and bewitching ride…
As many of you know, I got into this wacky world of nutrition because I was convinced everyone simply had a Mg-deficiency — thus was borne my wellness quest AND exposed my nutritional/metabolic naiveté…
I have journeyed for the last 7 years to make sense of this dynamic, with stops to better understand the dynamics of Na/K, Vitamin-D, Copper toxicity/dysregulation, and Ceruloplasmin metabolism… All was going reasonably well until the Universe dropped the Ace-in-the-Hole: Iron Overload…
And as I pursue this Rabbit-hole with a vengeance, I NOW realize WHY Magnesium is getting hosed, and WHY Copper is sooooo dysregulated. And the mechanics of understanding Oxidative Stress! and the role of Copper-dependent enzymes (SOD, GSH [GSH-Px], and CAT) to STOP this “Rusting” process, and the role of Iron to CREATE Free Radicals (ROS) is legendary in the research labs around the globe.
OK, so where’s he’s going today?…
Here are four (4) articles that I invite ALL who are serious about re-gaining their health and metabolic equilibrium:
o http://freetheanimal.com/2015/06/enrichment-theory-everything.html
o http://jn.nutrition.org/content/134/11/3171S.full.pdf+html
o http://circ.ahajournals.org/content/83/3/1112.full.pdf
If you take the time to read those article, which will keep you OFF the streets & Facebook for a good long while, what you’ll SOON discover is that we’re bring POISONED by Iron: in our food, properties of our water, Rx meds, vaccines, etc. The scale of it is mind-numbing to say the least.
For those that don’t know Joseph McCord, PhD, he and his Advisor, Irwin Fridovich, PhD discovered SOD: Superoxide Dismutase at Duke University in the late 1960’s… It is THE enzyme that is designed to neutralize the Superoxide radical (that’s an Oxygen molecule with an attitude!…). And as he points out in Equations #2 & #3 (known as the famous Haber/Weiss formula). In the absence of Copper-dependent SOD, it is a MAJOR source of ROS, esp. the much-feared Hydroxyl Radical that causes SOOOO much destruction of lipids on the cell membrane and proteins & DNA within the cell…
And what’s the gist of Jian et al (2009)?… That group of enterprising researchers is taking a very different look at the aging process, esp. the much discussed state of “Menopause!” Essentially, what they are challenging — and appropriately so — is that the core issues of this transition are equally related to Iron Overload, as they are to a lack of Estrogen…
That’s a VERY different way of viewing Menopause, and the key conditions that are associated with this:
o Hot Flashes…
o Osteoporosis…
o Skin Aging…
ALL brought to us by dysregulated Iron, courtesy of an organism that is swimming in bioUNavailable Copper and TOO LITTLE Ceruloplasmin, BOTH OF WHICH ARE ESSENTIAL for the proper regulation of ALL facets of Iron metabolism.
And folks who are chasing stratospheric levels of Ferritin, Calcium supplements, Fosamax, and HRT are apparently out of touch with what the leading research outlined ^^^^ is REALLY telling us… And when you factor in the Iron Fortification that is the underpinning of our Flour, then it will hit home.
Rest assured, there will be more posts and threads on this topic — I have NO doubt. This set of observations will cause rampant heartburn for all who take the time to read, reflect and re-evaluate their understanding of the “Aging” process. The Iron-y of this dynamic is captivating, just as any MAG-net is…
As always, I’ll look forward to the blow-back and repartee that this post will surely stimulate!…
A votre sante!
MORLEY M. ROBBINS
See Facebook Discussion at:
https://www.facebook.com/groups/MagnesiumAdvocacy/permalink/904403082961095/
